Comparing the Clinical Effects of Amiodarone and Propafenone in the Arrhythmia’s Treatment

  • Charmarke Ibrahim Cardiology Department, The First Affiliated Hospital of Xinjiang Medical University
  • Sakarie Hidig Cardiology Department, The First Affiliated Hospital of Xinjiang Medical University
  • Xiang Ma Cardiology Department, The First Affiliated Hospital of Xinjiang Medical University
DOI: https://doi.org/10.18282/l-e.v9i3.1562
Keywords: Arrhythmia, Propafenone, Amiodarone, Clinical Curative Effect

Abstract

Objective: To compare the clinical effects of Amiodarone and Propafenone in the treatment of arrhythmia. Methods: Choose our hospital 100 cases of patients with cardiac arrhythmias. We shall divided into control group (50 cases, Propafenone treatment) and treatment group (50 cases, Amiodarone therapy), to collect the curative effect of two groups of patients, adverse reactions, nausea and vomiting, dizziness, headache, low blood pressure, heart rate slow down) in accordance with the drug treatment and electrocardiogram (ecg) changes before and after the treatment (PR interphase, QT interphase, QRS duration). Results: Control group and the clinical curative effect of treatment group total effectiveness 98%, 86% respectively, the treatment group is significantly higher than the control group. Control group and treatment group the incidence of adverse reactions were 4%, 12%, treatment group was significantly lower than the control group, and two groups of patients duration are improved after treatmentstage PRinterval and QT, QRS.But the treatment group patients with stage PRinterval and QT,such as electrocardiogram QRS duration change was better than control group, which difference hasstatisticalsignificance (P < 0.05). Conclusion: Compared with propafenone, amiodarone in the treatment of arrhythmia patients has better therapeutic effect and higher safety, and improve the clinical symptoms of patients effectively. It is suggested to promote clinical practice.

References

Sun Hua. Comparison of efficacy of Propafenone and Amiodarone in the treatment of arrhythmia and its effect on serum HS- CRP [J]. Journal of Integrated Chinese and Western Medicine: Electronic Edition, 2017, 7(030): 41–41.

Liu Rong-kui. Comparative study on clinical efficacy and safety of Amiodarone and Propafenone in the treatment of arrhythmia [J]. Journal of Practical Cardio-Cerebral and Pulmonary Vascular Diseases, 2016, 24(005): 62–64.

Jia Dongmei, Bai Chunmei. Comparative Analysis of efficacy of Amiodarone and Propafenone in the treatment of arrhythmia [J]. Medical and Health (Abstract), 2016, 000(002): 00056.

Li Ke, Wei Yiyong, Cao Song, et al. Comparative study on the effect of Propafenone and Amiodarone in the treatment of arrhythmia [J]. Chinese Journal of Cardiovascular Disease, 2017, 5(012): 43–44.

Xu Yunyao, Chen Youlian, Huang Shian. Comparison of the clinical efficacy of Propafenone and Amiodarone in the treatment of arrhythmia patients, and the effect on cardiac function indicators and serum hypersensitive C-reactive protein [J]. Knowledge of cardiovascular disease prevention and control (second half), 2020, 010(001): 26–28.

Zhang Weiying. Comparison of the efficacy of Propafenone and Amiodarone in the treatment of arrhythmia and its effect on serum HS-CRP [J]. Frontiers in Medicine, 2017, 007(006): 116–117.

Published
2020-12-29
Issue
Vol. 9 No. 3 (2020)

Authors contributing to this journal agree to publish their articles under the  Creative Commons Attribution-Noncommercial 4.0 International License, allowing third parties to share their work (copy, distribute, transmit) and to adapt it, under the condition that the authors are given credit, that the work is not used for commercial purposes, and that in the event of reuse or distribution, the terms of this license are made clear. With this license, the authors hold the copyright without restrictions and are allowed to retain publishing rights without restrictions as long as this journal is the original publisher of the articles.