Vol. 5 No. 2 (2023)

Open Access

Original Research Article

Article ID: 2350

Analysis of Risk Factors for Perioperative Sepsis in Urinary Calculi

by Zhuo Li, Huan Han, Yuyao Zhai, Peng Zhang, Juan Ma, Wanli Duan

Reports in Clinical Studies and Medicine, Vol.5, No.2, 2023; 76 Views, 18 PDF Downloads

The risk factors for perioperative sepsis were investigated in patients with urinary calculi in order to propose targeted interventions. Patients discharged from a 3A hospital with a diagnosis of urinary calculi co-infection in 2020 were retrospectively analyzed and grouped according to whether sepsis occurred in the perioperative period, and the clinical data of the two groups were compared. A total of 435 patients discharged with a diagnosis of urinary calculi co-infection were collected, and urogenic sepsis occurred in 23 cases, with an overall incidence of 5.3%. Univariate analysis showed that gender, abnormal blood leukocyte count on admission, positive urine culture results, carbon dioxide binding capacity and blood creatinine values were risk factors for the development of urogenital sepsis in patients with urinary calculi after surgery ( P<0 .05), while preoperative prophylaxis was a protective factor ( P <0.05). Multifactorial logistic regression analysis showed that preoperative blood leukocyte values, urine culture results, and blood creatinine values were independent risk factors for the development of urogenic sepsis in patients with urinary calculi after surgery.

Open Access

Original Research Article

Article ID: 2236

The Effects of Levodopa on Albinism

by Yi Hao, Huina Ma, Siyuan Wang, Hairu Yan, Wei Zhou

Reports in Clinical Studies and Medicine, Vol.5, No.2, 2023; 75 Views, 15 PDF Downloads

Albinism, a refractory disease with reduced pigmentation. And it has caused great distress to the patient's body and mind. How to treat the disease is a troubling problem in history. Levodopa, a medicine is used when needed to treat the return of Parkinson’s symptoms. However, since the last century, some doctors have proposed using levodopa to treat albinism. The results of the experiment were not very significant. We research the effects of levodopa on albinism from mechanism of action, clinical trial, molecular mechanism and clinical studies. We find that levodopa has only a weak or no effect on fetuses with albinism.