https://ojs.piscomed.com/index.php/rcsm <table><tbody><tr style="vertical-align: top;"><td style="text-align: justify;"><p>The Journal of Reports in Clinical Studies and Medicine is a peer-reviewed, open access journal that offers practicing healthcare professionals in-depth useful reviews and research clinical trials regarding the recent interventional medical and therapeutic approaches. The Journal aims to publish original researches and reviews from the globe but especially focuses on clinical trials that are conducted in developing countries. We know that medical practice is developing in a very fast way and most researchers wish to get a rapid decision about their work, so the review process for all submitted articles will be completed within 5 weeks.</p></td><td><div id="cover_section"><a title="Clinical Studies" href="/index.php/rcsm" target="_self"> <img id="cover-img" src="/public/journals/6/journalThumbnail_en_US.jpg" alt="Clinical Studies" align="right" /> </a></div><div id="issn_section"><span class="issn_num">ISSN(Online): 2661-4006<br /></span><br /> <img src="/public/site/Open_Access.png" alt="" height="20px" /></div></td></tr></tbody></table> PiscoMed Publishing Pte Ltd en-US Reports in Clinical Studies and Medicine 2661-4006 <p>Authors contributing to this journal agree to publish their articles under the <a href="http://creativecommons.org/licenses/by-nc/4.0" target="_blank">Creative Commons Attribution-Noncommercial 4.0 International License</a>, allowing third parties to share their work (copy, distribute, transmit) and to adapt it, under the condition that the authors are given credit, that the work is not used for commercial purposes, and that in the event of reuse or distribution, the terms of this license are made clear. With this license, the authors hold the copyright without restrictions and are allowed to retain publishing rights without restrictions as long as this journal is the original publisher of the articles.</p><p><img src="/public/site/by-nc.png" alt="" height="30px" /></p> https://ojs.piscomed.com/index.php/rcsm/article/view/2350 The risk factors for perioperative sepsis were investigated in patients with urinary calculi in order to propose targeted interventions. Patients discharged from a 3A hospital with a diagnosis of urinary calculi co-infection in 2020 were retrospectively analyzed and grouped according to whether sepsis occurred in the perioperative period, and the clinical data of the two groups were compared. A total of 435 patients discharged with a diagnosis of urinary calculi co-infection were collected, and urogenic sepsis occurred in 23 cases, with an overall incidence of 5.3%. Univariate analysis showed that gender, abnormal blood leukocyte count on admission, positive urine culture results, carbon dioxide binding capacity and blood creatinine values were risk factors for the development of urogenital sepsis in patients with urinary calculi after surgery (<em>P&lt;0</em>.05), while preoperative prophylaxis was a protective factor (<em>P</em>&lt;0.05). Multifactorial logistic regression analysis showed that preoperative blood leukocyte values, urine culture results, and blood creatinine values were independent risk factors for the development of urogenic sepsis in patients with urinary calculi after surgery. Zhuo Li Huan Han Yuyao Zhai Peng Zhang Juan Ma Wanli Duan Copyright (c) 2023 Yi Hao, Huina Ma, Siyuan Wang, Hairu Yan, Wei Zhou https://creativecommons.org/licenses/by-nc/4.0 2023-11-11 2023-11-11 5 2 21 24 10.18282/rcsm.v3.i2.2350 https://ojs.piscomed.com/index.php/rcsm/article/view/2236 <p align="left">Albinism, a refractory disease with reduced pigmentation. And it has caused great distress to the patient's body and mind. How to treat the disease is a troubling problem in history. Levodopa, a medicine is used when needed to treat the return of Parkinson’s symptoms. However, since the last century, some doctors have proposed using levodopa to treat albinism. The results of the experiment were not very significant. We research the effects of levodopa on albinism from mechanism of action, clinical trial, molecular mechanism and clinical studies. We find that levodopa has only a weak or no effect on fetuses with albinism.<strong></strong></p> Yi Hao Huina Ma Siyuan Wang Hairu Yan Wei Zhou Copyright (c) 2023 Yi Hao, Huina Ma, Siyuan Wang, Hairu Yan, Wei Zhou https://creativecommons.org/licenses/by-nc/4.0 2023-11-11 2023-11-11 5 2 17 20 10.18282/rcsm.v3.i2.2236