Circular RNA (circRNA) and YAP in tumor: A review

  • Xu Li Department of Pulmonary, Capital Medical University Electric Power Teaching Hospital
  • Xiaodong Tian Chinses PLA General Hospital
  • Xiangdong Mu Pulmonary Department, Beijing Tsinghua Changgung Hospital
  • Zhenzhen Liang Department of Oncology, Capital Medical University Electric Power Teaching Hospital
  • Xiaohui Xu Department of Oncology, Capital Medical University Electric Power Teaching Hospital
  • Haiyun Yu Department of Oncology, Capital Medical University Electric Power Teaching Hospital
Ariticle ID: 851
444 Views, 28 PDF Downloads
Keywords: Tumor, circRNA, YAP

Abstract

Background: Circular Ribonucleic Acid (circRNA) is a type of RNA that has been found in recent years and is a closed loop structure widely found in eukaryotic cells. Present situation: The circRNA is stable in nature, highly conserved and tissue and disease specific, and regulates target gene expression at the transcriptional or posttranscriptional level, which is related to the occurrence and development of tumors. YAP (Yes-associated protein) is the main effector of Hippo signaling pathway. It is found that YAP level is closely related to cell proliferation and apoptosis, tissue organ size control and tumorigenesis. Aim: to study the correlation between circRNA and YAP in tumors.

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Published
2023-10-15
How to Cite
Li, X., Tian, X., Mu, X., Liang, Z., Xu, X., & Yu, H. (2023). Circular RNA (circRNA) and YAP in tumor: A review. General Surgery, 7(1), 23-29. https://doi.org/10.18282/gs.v3i1.851
Section
Review