Efficacy of Acupuncture in Treatment of Parkinson's Disease with Orthostatic Hypotension: A Randomized Controlled Clinical Trial

Yue Liu, Yun Dang, Peng Tang, Jiaxin Zhao, Peipei Li, Hong Wang, Dongliang Wang


Objective: To evaluate the therapeutic effect and safety of acupuncture on Parkinson's disease (PD) with orthostatic hypotension (OH) patients. Methods: A randomized controlled clinical trial was used to observe the efficacy of acupuncture in the treatment of 51 PD with OH patients. The observation time was 1 week. Results: After 1 week of acupuncture treatment, the blood pressure and blood flow velocity of left middle cerebral artery of the treatment group increased compared with the control group, and the difference was statistically significant (P<0.05); the visual vertigo analog scale (VVAS) of the treatment group decreased compared with the control group, and the difference was also statistically significant (P<0.05). After 1 week of acupuncture treatment, the heart rate of the treatment group increased compared with the control group, and the modified Rankin score (mRS) of the treatment group decreased compared with the control group, but there was no statistical difference (P>0.05). There were no serious adverse events and adverse reactions during the observation period. Conclusion: Acupuncture is effective and safe in the treatment of PD with OH.


Parkinson's Disease; Orthostatic Hypotension; Acupuncture; Randomized Controlled Clinical Trial

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DOI: http://dx.doi.org/10.18282/pmr.v10i2.2772


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