Efficacy and Safety of Paclitaxel and Cisplatin in the Treatment of Advanced Ovarian Cancer by Different Means of Administration

  • Datian Fu Department of Pharmacy, Hainan Women and Children's Medical Center
Keywords: Paclitaxel, Advanced Ovarian Cancer, Safety Study

Abstract

In the treatment of advanced ovarian cancer, paclitaxel and cisplatin are administered in different ways. This paper discusses the efficacy and safety of this approach. Methods: Data were searched through literature, and classified discussion was conducted on this basis. The experimental group and the control group were treated in different ways, and the analysis was carried out by way of comparison, so as to explore the therapeutic effect of drug administration route on advanced ovarian cancer patients. Results: After the completion of the statistical survey, the experimental group was compared with the control group by intravenous infusion after using the new administration method. In terms of the results, the intraperitoneal infusion method had a better effect on the treatment of patients. In terms of the data, this method could effectively improve the long-term survival rate of patients. However, in terms of hepatorenal and peripheral neurotoxicity, intraperitoneal perfusion was more toxic. In terms of musculoarthralgia, the type of intraperitoneal perfusion, has a much greater effect on the patient. Conclusions: Intraperitoneal perfusion has positive therapeutic effects in patients with advanced ovarian cancer, but it is more burdsome to the body. Therefore, in the process of use, we should make comprehensive selection according to the specific situation of patients.

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Published
2021-09-01
Section
Original Research Articles