Evaluation de l’expression de la fatigue liée au cancer : comparant l’expression de la fatigue chez les patients atteints de cancer, chez les patients touchés par d’autres maladies chroniques et chez les individus en bonne santé
Assessment of Cancer-Related Fatigue Expression: Comparing the Expression of Fatigue in Patients with a History of Cancer, Patients with Other Chronic Diseases, and Healthy Individuals
Abstract
Aims: We aimed to compare cancer survivors’ fatigue expression with that of the general population and examine psychobiological factors associated with fatigue. Procedure: In this quantitative, transversal study, we analyzed clinical and sociodemographic indicators of 389 participants (68.38% females): 148 cancer survivors on active treatment, 55 disease-free survivors, 75 patients with another chronic disease, and 111 healthy individuals. Results: Fatigue was expressed dissimilarly in patients with a previous history of cancer and participants without a history of cancer. Survivors on active treatment reported significantly higher levels of fatigue than the other clinical status groups. Nonetheless, some level of cancer-related fatigue persisted, in a similar pattern, after active treatment into the survivorship phase. Disease-free survivors showed significantly lower vigor levels when compared to patients with other chronic diseases. Psychological distress and daytime sleepiness emerged as transdiagnostic factors associated with fatigue. Conclusion: Cancer-related fatigue may have a unique pattern, characterized by reduced endurance and muscle weakness. In the present study, psychological distress and daytime sleepiness are associated with cancer-related fatigue. These findings suggest the pertinence of future studies examining whether interventions targeting those factors may help manage this burdensome complaint.
Résumé
Objectif: L’objectif de l’étude fut de comparer la fatigue ressentie par les patients du cancer par rapport à celle de la population en générale, ainsi que d’examiner les facteurs de risque psychobiologiques associés à la fatigue. Matériel et méthodes: Dans cette étude quantitative et transversale, nous avons analysé les indicateurs cliniques et sociodémographiques de 389 participants (68.38% de femmes) : 148 patients du cancer sous traitement actif, 55 patients dans l’après-traitement d’un cancer, 75 patients atteints d’une autre maladie chronique et 111 personnes en bonne santé. Résultats: La fatigue s’exprimait de manière différente chez les patients ayant des antécédents de cancer et chez les participants sans antécédent de cancer. Les patients sous traitement actif ont signalé des niveaux de fatigue significativement plus élevés que les autres groupes. Néanmoins, une certaine fatigue associée au cancer a persisté, dans un cadre similaire, après un traitement actif et jusqu’à la phase de survie. Les patients dans l’après-traitement d’un cancer ont montré des niveaux de vigueur significativement inférieurs à ceux des patients atteints de maladies chroniques. La détresse psychologique et la somnolence diurne sont apparues comme des facteurs transdiagnostiques associés à la fatigue. Conclusion: La fatigue liée au cancer peut avoir un cadre unique, caractérisé par une endurance réduite et une faiblesse musculaire. Dans la présente étude, la détresse psychologique et la somnolence diurne sont associées à la fatigue liée au cancer. Ces résultats suggèrent la pertinence d’études futures examinant si des interventions ciblant ces facteurs peuvent aider à gérer cette plainte pesante.
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