Effectiveness of psychological interventions on treatment adherence and quality of life in breast cancer survivors: A systematic review and meta-analysis

Houyan  Li; Guandong  Song; Bin  Xiao; Quan  Gong

doi:10.18282/po3599

Houyan Li School of Humanities and Law, Northeastern University, Shenyang 110169, China; President’s Office, Shenyang Urban Construction University, Shenyang 110167, China
Guandong Song School of Humanities and Law, Northeastern University, Shenyang 110169, China
Bin Xiao School of Humanities and Law, Northeastern University, Shenyang 110169, China
Quan Gong Institute of General Education, Shanghai Academy of Educational Sciences, Shanghai 200032, China

Article ID: 3599

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Keywords: psychological interventions; breast cancer survivors; treatment adherence; quality of life; systematic review; meta-analysis

Abstract

Objective: To evaluate the impact of psychological interventions on treatment adherence and quality of life in breast cancer survivors. Methods: A systematic review and meta-analysis of 42 randomized controlled trials (2002–2023). Interventions included Cognitive-Behavioral Therapy (CBT), Mindfulness-Based Interventions (MBI), and Supportive-Expressive Group Therapy (SEGT). Primary outcomes assessed were treatment adherence and quality of life. Key Findings: Treatment Adherence: Psychological interventions significantly improved adherence (RR = 1.27, 95% CI: 1.18–1.37), with CBT showing the largest effect (RR = 1.35). Interventions lasting ≥8 weeks were more effective. Quality of Life: Moderate improvements were observed (SMD = 0.45, 95% CI: 0.36–0.54), with MBI having the strongest impact (SMD = 0.56). Interventions of ≥12 weeks yielded better outcomes. Meta-regression: Longer interventions were linked to larger effects for both adherence and quality of life. Conclusions: CBT and MBI significantly enhance treatment adherence and quality of life in breast cancer survivors, especially with longer interventions. Psychological support should be integrated into comprehensive cancer care.

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