Effectiveness of psychological interventions on treatment adherence and quality of life in breast cancer survivors: A systematic review and meta-analysis
Abstract
Objective: To evaluate the impact of psychological interventions on treatment adherence and quality of life in breast cancer survivors. Methods: A systematic review and meta-analysis of 42 randomized controlled trials (2002–2023). Interventions included Cognitive-Behavioral Therapy (CBT), Mindfulness-Based Interventions (MBI), and Supportive-Expressive Group Therapy (SEGT). Primary outcomes assessed were treatment adherence and quality of life. Key Findings: Treatment Adherence: Psychological interventions significantly improved adherence (RR = 1.27, 95% CI: 1.18–1.37), with CBT showing the largest effect (RR = 1.35). Interventions lasting ≥8 weeks were more effective. Quality of Life: Moderate improvements were observed (SMD = 0.45, 95% CI: 0.36–0.54), with MBI having the strongest impact (SMD = 0.56). Interventions of ≥12 weeks yielded better outcomes. Meta-regression: Longer interventions were linked to larger effects for both adherence and quality of life. Conclusions: CBT and MBI significantly enhance treatment adherence and quality of life in breast cancer survivors, especially with longer interventions. Psychological support should be integrated into comprehensive cancer care.
Copyright (c) 2024 Houyan Li, Guandong Song, Bin Xiao, Quan Gong
This work is licensed under a Creative Commons Attribution 4.0 International License.
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