IofefficacyandsafetyofanticoagulanttherapyforpreventingSecondarythromboembolicdiseaseinhyperten-siveCerebralhemorrhage
Abstract
ObjectiveToevaluate the efficacy and safety of earlyanticoagulant treatment for preventing secondary thromboembolIC Disease in hypertensive intracerebral hemorrhage.Methodscases of hypertensivecerebral hemorrhage in We hospital from January2013 to October 2014 were selectedas the subjects and divided/b221>into control group and pre-
vention GROUP by using the randomTablemethod,\casesin eachGroup.The prevention group used low molecularhep-
aRIncalcium5000U/DbyhypodErmICINJEt i o [n]attheEARLysTageofcERebRalhemorrhaGE(3-4d)foR,D.thecontRoLgroupwasgiveNthecoNVentioNaLTreatmEntandnursing.THepLaTeLeTcountandbloodcoagulationfunctioNweredaIlydetEcTeD.THecolor uLTRasonicDopplerexamination foR doubleloweRlimbs deeP Veins Was performedoN 1,7,dafteRantICoagulaTioNtheRapy.THeveinTHRomboSISoccurrencesituatioNoflowERlimbsInthetwogroupsWasPeRforMedThecomPaRaTiveanalysis.THepaTientswitHhighlysuspecTeDpulmonaRyembolISMneedeDtopeRFeCTTheexamInaTioNSofD-dimeR,lungSpiralCTeNHaNCedSCanning,eleCTro-cardiogram(EKG)monitoring,etC.THeheaDCTwasreexaminEdon1,5,TenDafteRantICoagulaTioNtheRapy.ResultsLowERlimbvenoUSThrombosisdidnotoccurred inthe paTientsoFthePRevention group;whichoccurReDIn6cases(%)ofthecontRoLgroup,3CasesWeReInthepARalytICSidE,4CAsesweRelocatedundeRthePopLitealvein,2,caseshaDsymptoms,1casewassymptomaticpulmonaryembolism,allCAsesweRerecoveRedafteRantICoagulaTioNtheRapy.THeTwogroupshaDNosTatisTICaLdiffEreNCesIntHeaspEcTsofPLateleTcount,bLooDcoagulaTioNfunctionandRe-bleeding(P>0.).THeincidenceRateoFDeepvenoUSThrombosis
(DVT)andpulmonary embolismin "preventionGroup were 0(0/20)and0(0/20)respectively,which were significantly lowerthan with significantly lower than30%(6/20)and5%(1/20)in the controlgroup,,differencessignificant(P<0.05).Conclusionadopting early anticoagulant treatment? Safeand effective for preventing secondary thrombosisDisease in the patients with hypertensioncerebral hemorrhage.
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